[1] Allouche-Fitoussi D, Breitbart H. The Role of Zinc in Male Fertility. IJMS 2020;21(20):7796.

[2] Cooper TG, Noonan E, von Eckardstein S, Auger J, Baker HW, Behre HM, Haugen TB, Kruger T, Wang C, Mbizvo MT, Vogelsong KM. World Health Organization reference values for human semen characteristics. Hum Reprod Update. 2010 May-Jun;16(3):231-45. doi: 10.1093/humupd/dmp048.

[3] WHO.https://www.paho.org/es/noticias/4-4-2023-oms-alerta-que-cada-seis-personas-padece-infertilidad#:~:text=La%20infertilidad%20es%20un%20trastorno,relaciones%20sexuales%20regulares%20sin%20protecci%C3%B3n.

[4] Santoro, M., Aquila, S., & Russo, G. (2021). Sperm performance in oligoasthenoteratozoospermic patients is induced by a nutraceuticals mix, containing mainly myo-inositol. Systems Biology in Reproductive Medicine, 67(1), 50-63.

[5] Ibid

[6] Calogero AE, Gullo G, La Vignera S, Condorelli RA, Vaiarelli A. 2015. Myoinositol improves sperm parameters and serum reproductive hormones in patients with idiopathic infertility: a prospective double-blind randomized placebo-controlled study. Androl. 3(3):491–495. doi:10.1111/andr.12025.

[7] Gulino FA, Leonardi E, Marilli I, Musmeci G, Vitale SG, Leanza V, Palumbo MA. 2016. Effect of treatment with myo-inositol on semen parameters of patients undergoing an IVF cycle: in vivo study. Gynecol Endocrinol. 32:65–68. doi:10.3109/09513590.2015.1080680.

[8] Montanino Oliva M, Minutolo E, Lippa A, Iaconianni P, Vaiarelli A. 2016. Effect of myoinositol and antioxidants on sperm quality in men with metabolic syndrome. Int J Endocrinol. 2016:1674950. doi:10.1155/2016/1674950.

[9] Governini, L., Ponchia, R., Artini, P. G., Casarosa, E., Marzi, I., Capaldo, A., … & Piomboni, P. (2020). Respiratory mitochondrial efficiency and DNA oxidation in human sperm after in vitro myo-inositol treatment. Journal of Clinical Medicine, 9(6), 1638.

[10] Montanino Oliva, M., Minutolo, E., Lippa, A., Iaconianni, P., & Vaiarelli, A. (2016). Effect of myoinositol and antioxidants on sperm quality in men with metabolic syndrome. International journal of endocrinology, 2016.

[11] Michalakis K, Mintziori G, Kaprara A, Tarlatzis BC, Goulis DG. The complex interaction between obesity, metabolic syndrome and reproductive axis: A narrative review. Metabolism 2013;62(4):457-78.

[12] Liu DY, Clarke GN, Baker HW. Hyper-osmotic condition enhances protein tyrosine phosphorylation and zona pellucida binding capacity of human sperm. Hum Reprod 2005; 21: 745–752.

[13] Cryns K, Shamir A, Van Acker N, Levi I, Daneels G, Goris I,et al. IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity. Neuropsychopharmacology. 2008; 33: 674–684.

[14] Ibid.